People living with SCD pictured may or may not have received CASGEVY.
Ready to find out if CASGEVY may help end your vaso-occlusive crises, or VOCs*?
The first step is sitting down with your healthcare provider and your support network to discuss CASGEVY. We've put together some questions to think through and discuss with your loved ones and care team.
To get ideas on some important questions to consider, select a topic below.
Healthcare Provider Discussion
Questions for your healthcare provider
- How does gene therapy work?
- Is gene therapy a good treatment option for sickle cell disease?
- How do I know if CASGEVY is right for me?
- How does CASGEVY stop vaso-occlusive crises (VOCs)?
- Will CASGEVY fix the organ damage I already have?
- How safe is CASGEVY?
- How does CASGEVY help the body make working red blood cells?
- Why don’t I need a donor with CASGEVY?
- What are the steps to receiving CASGEVY? How long does it take?
- Will treatment be covered by insurance? What will I need to pay?
- What else should I consider when deciding on CASGEVY?
Self-Reflections
Questions to ask yourself before starting CASGEVY
- How could treating with CASGEVY change my life with sickle cell disease?
- How will I manage my personal responsibilities (home, work, school, family) during the treatment process?
- Whom can I lean on for support throughout my journey?
- The chemotherapy given before CASGEVY can affect my ability to have children. Is fertility preservation something I want to consider?
- Am I prepared to start the treatment journey with CASGEVY and everything that is involved?
- How will CASGEVY affect my identity as someone living with sickle cell disease?
Caregiver Considerations
Questions for caregivers supporting a loved one
- What information do I need to help my loved one decide if CASGEVY is right for them?
- What are the different ways I will need to support my loved one on their treatment journey?
- How will my responsibilities as a caregiver change once my loved one starts CASGEVY? Do I need extra support?
- How can I make sure I am there for my loved one throughout their journey? What plans should I make so that I can support them?
- What resources or support groups are available to me? How do I also care for myself during this time?
- How can I help my loved one think through future considerations, like the possible impact on fertility?
*In clinical studies, severe VOCs, or vaso-occlusive crises, were defined as a pain event requiring a visit to a medical facility and pain medication or a red blood cell (RBC) transfusion, acute chest syndrome, priapism (persistent and often painful erection of the penis for more than 2 hours), or splenic sequestration (blood trapped in the spleen).
